TECHNOLOGIES 2026
Technologies marked with an * will be presented orally.
Cardiovascular
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A4
ICR-001: First-in-class dual action oral therapy for secondary stroke prevention
Dr Szandor Simmons, Prof. Wolfgang Kübler, Erik Asmus, Prof. Robert Szulcek, Prof. Robert Preissner
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A8*
Inhibition of TGFβ1-induced Long Non-Coding RNAs Prevents Cardiac Fibrosis
Prof. Thomas Thum, Prof. Christian Bär
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C4*
Novel Treatment of Diseases Associated with or Caused by Mitochondrial Dysfunction
Dr Jaya Krishnan, Dr Arka Provo Das
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M5*
Development of Gasdermin D Inhibitors for the Treatment of Stroke and Reperfusion Injury with an upside in ANCA and Autoimmune Diseases
Prof. Arturo Zychlinsky, Prof. Herbert Waldmann, Prof. Matthias Gunzer, Dr Bert Klebl
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M6*
Development of GRK5 Inhibitors for the Treatment of Acute and Chronic Cardiovascular Diseases
Prof. Axel Ullrich, Prof. Kristina Lorenz, Prof. Johannes Backs, Dr Bert Klebl
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P4
Bidirectional Nanobody System For Fibrinolysis
Prof. Bernd Pötzsch, Dr Nasim Shahidi Hamedani, Eva-Maria Klein, Dr Jens Müller, Dr Paul-Albert König, Prof. Florian Ingo Schmidt, Jan Moritz Paul Tödtmann
Device
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B1*
OrbitaTreat - A Device and System for a Minimally Invasive Orbital Floor Fracture Implantation
Prof. Thomas Schratzenstaller, Dr Moritz Burger, Prof. Thomas Kühnel
Diagnostics
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A7*
FAP-Targeted Dual Imaging for Guided Cancer Surgery
Prof. Clemens Decristoforo, Giacomo Gariglio, Dr Christine Rangger, Dr Milos Petrik
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H1*
EpiPhaGO: Blood Test for Alzheimer’s Risk Detection
Dr Matthias Prestel, Prof. Jochen Herms, Dr Sabina Tahirovic
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I1
KidneyGuard
Jan Štovíček, Daniel Křížek, Jan Vyčítal
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I6
Lab On Card – Miniaturized ELISA on Microfluidic Chip
Josef Haščyn, Dr Tomas Riedel, Dr Andres de los Santos, Dr Marek Škereň, Dr Zuzana Riedelova, Dr Michal Pohludka
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I7*
SeveriDx™ Prediction Kit
Prof. Stanislav Kmoch, Dr Lenka Piherová, Dr Hana Hartmannová , Dr Michal Pohludka, Dr Katerina Solcova
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M3*
Optical Lung Function Measurement by Non-Invasive Chest Motion Tracking
Prof. Christian Dullin, Prof. Frauke Alves, Dr Angelika Svetlove
Gene & Cell Therapy, Gene Editing
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A8*
Inhibition of TGFβ1-induced Long Non-Coding RNAs Prevents Cardiac Fibrosis
Prof. Thomas Thum, Prof. Christian Bär
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H5
SynTra – Synthetic Transposons for Non-Viral Gene Transfer
Dr Michael Fichtner
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P3
Improved Lymphocyte Effector Function
Prof. Philipp Lang, Dr Haifeng Xu, Julia Werner
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Q4
Phase I Best-in-Class DNA-Dependent Protein Kinase (DNA-PK) Inhibitor: AZD7648
Dr Maurice Raymond, Dr Frederick Woolf Goldberg, Dr Verschoyle Finlay, Dr Attilla Kuan Tsuei Ting
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Q6*
iTAG (“Inducible and TArgeted protein DeGradation”) Platform: Drug‑Inducible Degron Tags for Adoptive Cell‑Based Immunotherapies
Prof. Ian Collins, Prof. Louis Chesler, Prof. John Anderson, Dr Yann-Vai Le Bihan
Immune/Autoimmune
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A2
Novel CARs for the Treatment of Multiple Sclerosis and Alzheimer´s Disease
Prof. Matthias Hardtke-Wolenski, Dr Valerie Sätzler, Prof. Elmar Jäckel, Dr Tobias Riet, Prof. Michael Hust, Saskia Helmsing
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A6*
CRISPR-Cas9 Mediated Proteinase 3 Autoantigen Deletion as a Treatment Strategy for ANCA-Associated Vasculitis
Dr Uwe Jerke, Dr Claudia Eulenberg-Gustavus, Dr Dimitrios Laurin Wagner, Prof. Ralph Kettritz
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M5*
Development of Gasdermin D Inhibitors for the Treatment of Stroke and Reperfusion Injury with an upside in ANCA and Autoimmune Diseases
Prof. Arturo Zychlinsky, Prof. Herbert Waldmann, Prof. Matthias Gunzer, Dr Bert Klebl
Infection
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A1
ASO-Based mRNA Silencing Technology for Phage
Prof. Jörg Vogel, Prof. Milan Gerovac, Dr Svetlana Durica-Mitic
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A5*
TReAT - A Novel Tacrolimus-Resistant Antiviral T-Cell-Therapy
Dr Leila Amini, Dr Michael Schmück-Henneresse, Prof. Petra Reinke, Prof. Hans-Dieter Volk, Dr Dimitrios Laurin Wagner
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C1
Dense Immune
Dr Zahra Ghodratian, Dr Azelarab Terkemani, Prof. Bodo Plachter, Prof. Niels Lemmermann
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C3*
mRNA-Based Therapeutic Vaccine for Functional Cure of Chronic Hepatitis B
Dr Maria Jose Limeres, Dr German Islan, Prof. Stephan Gehring, Dr Maximiliano Cacicedo
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H3
Development of a Live Biotherapeutic Product to Promote Gut Decolonization of Multi-Drug Resistant and Pathogenic Bacteria
Prof. Till Strowig, Dr Lisa Osbelt-Block, Dr Marie Wende
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I6
Lab On Card – Miniaturized ELISA on Microfluidic Chip
Josef Haščyn, Dr Tomas Riedel, Dr Andres de los Santos, Dr Marek Škereň, Dr Zuzana Riedelova, Dr Michal Pohludka
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I7*
SeveriDx™ Prediction Kit
Prof. Stanislav Kmoch, Dr Lenka Piherová, Dr Hana Hartmannová , Dr Michal Pohludka, Dr Katerina Solcova
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P2*
Pan-Tuberculosis Signature
Prof. Jan Rybniker, Dr Isabelle Suarez, Dr Sebastian Theobald, Dr Thomas Ulas, Dr Marc Beyer, Dr Kilian Dahm
Metabolism
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C4*
Novel Treatment of Diseases Associated with or Caused by Mitochondrial Dysfunction
Dr Jaya Krishnan, Dr Arka Provo Das
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H4
ComboMiR: Combinatorial microRNA Therapeutics for Diabetic Complications
Prof. Stephan Herzig, Dr Manuel Gil-Lozano, Dr Estefania Simoes Fernandez, Dr Ana Jimena Alfaro Nuñez
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I2
Lipidera
Prof. Petr Pávek, Dr Radim Nencka
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I3*
MenoFitX - Post-Menopausal Obesity Treatment for Healthy Aging
Dr Lenka Maletinska, Dr Sonia Cantel, Dr Jan Skace, Dr Katarina Psenakova
Neurology
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A2
Novel CARs for the Treatment of Multiple Sclerosis and Alzheimer´s Disease
Prof. Matthias Hardtke-Wolenski, Dr Valerie Sätzler, Prof. Elmar Jäckel, Dr Tobias Riet, Prof. Michael Hust, Saskia Helmsing
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H1*
EpiPhaGO: Blood Test for Alzheimer’s Risk Detection
Dr Matthias Prestel, Prof. Jochen Herms, Dr Sabina Tahirovic
Oncology
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A7*
FAP-Targeted Dual Imaging for Guided Cancer Surgery
Prof. Clemens Decristoforo, Giacomo Gariglio, Dr Christine Rangger, Dr Milos Petrik
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B2*
Desaminotyrosine (DAT) as a GvHD Preventive/Therapeutic Adjuvant and Immunotherapy Outcome Predictor
Dr Erik Thiele Orberg, Prof. Hendrik Poeck, Sascha Göttert
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C2
DARPin-based stabilization of p53 for cancer therapy
Prof. Volker Dötsch, Dr Andreas Jörger
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H2*
Real-Time Magnetic Resonance Imaging Guided Proton Therapy (rt-MRiPT)
Prof. Aswin Hoffmann, Prof. Esther Troost, Dr Sergej Schneider
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H5
SynTra – Synthetic Transposons for Non-Viral Gene Transfer
Dr Michael Fichtner
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M4*
RNA-Binding Small Molecules with a Rigid Core (R-Score)
Prof. Peng Wu, Mao Jiang, Dr Yang Liu, Daniel Hoesle
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P3
Improved Lymphocyte Effector Function
Prof. Philipp Lang, Dr Haifeng Xu, Julia Werner
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Q1*
First-in-Class Lead PROTAC ERK5 Degrader for Treatment of Solid Tumours
Dr Katherine Finnegan, Dr Sam Butterworth
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Q2*
CD74 as a Biomarker for Responsiveness to Cancer Immunotherapy
Prof. Francesca Ciccareli, Dr Amelia Acha-Sagredo, Dr Pietro Andrei
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Q4
Phase I Best-in-Class DNA-Dependent Protein Kinase (DNA-PK) Inhibitor: AZD7648
Dr Maurice Raymond, Dr Frederick Woolf Goldberg, Dr Verschoyle Finlay, Dr Attilla Kuan Tsuei Ting
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Q6*
iTAG (“Inducible and TArgeted protein DeGradation”) Platform: Drug‑Inducible Degron Tags for Adoptive Cell‑Based Immunotherapies
Prof. Ian Collins, Prof. Louis Chesler, Prof. John Anderson, Dr Yann-Vai Le Bihan
Others
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A10 SPIN-OFF
Bionebula: Bioluminescence Imaging Solutions
Dr Jian Cui, Dr Thomas Bischof
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E5
Extracellular Matrix (ECM)
Dr George Galea, Dr Muzamil Majid Khan
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H2*
Real-Time Magnetic Resonance Imaging Guided Proton Therapy (rt-MRiPT)
Prof. Aswin Hoffmann, Prof. Esther Troost, Dr Sergej Schneider
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I1
KidneyGuard
Jan Štovíček, Daniel Křížek, Jan Vyčítal
Pneumology
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M3*
Optical Lung Function Measurement by Non-Invasive Chest Motion Tracking
Prof. Christian Dullin, Prof. Frauke Alves, Dr Angelika Svetlove
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P4
Bidirectional Nanobody System For Fibrinolysis
Prof. Bernd Pötzsch, Dr Nasim Shahidi Hamedani, Eva-Maria Klein, Dr Jens Müller, Dr Paul-Albert König, Prof. Florian Ingo Schmidt, Jan Moritz Paul Tödtmann
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R3*
Allosteric Modulation of Transglutaminase 2 to Treat Progressive Pulmonary Fibrosis
Prof. Ulf Simonsen, Dr Gökay Albayrak
Tools
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A1
ASO-Based mRNA Silencing Technology for Phage
Prof. Jörg Vogel, Prof. Milan Gerovac, Dr Svetlana Durica-Mitic
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A3
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A9 SPIN-OFF
Silicone oil-free syringe adapter - "PURINGE"
Felix Hehnen, Tim Bierewirtz, Paul Geus
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E1
Machine Learning and Multi-Omics for Predicting Chemical Toxicity
Dr Jessica Ewald
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E2
Proximity Assay
Dr Sagar Bhogaraju
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E3
Methods and Systems for Modulating RNA-Enzyme Complex Activity
Dr Eva Kowalinski
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E4*
VARIOMIS: Deconvoluting Genetic Diversity to De-Risk Drug Discovery
Dr James Stephenson
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H6*
DrugSeq Solutions - A First-In-Class Single-Cell Sequencing Platform
Dr Violaine Goidts, Dr Mona Göttmann, Dr Obada Alhalabi, Dr Emma Phillips
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I4*
Beyond Antibodies: Aptamers as Next Frontier in Diagnostics and Therapeutics
Dr Marek Ondrus, Prof. Michal Hocek
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I5*
Quantum Mechanical Scoring for Computational Structure-based Drug Design
Dr Adam Pecina, Dr Jan Řezáč, Dr Jindřich Fanfrlík, Dr Martin Lepšík
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I8*
ChemCell - Creating a Universal Anchoring Point on Living Cells for Conjugation of Functional Molecules
Dr Milan Vrabel, Dr Katarina Psenakova
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M1*
RiboSTS – Ribosome Signatures Targeted by High-Throughput Single-Cell Sequencing
Dr Matthew Kraushar, Dmitrii Zagrebin, Prof. Elke Deuerling, Dr Stefan Stefanov
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M2*
Generation of RNA Therapeutics by Conjugating NAD-Capped RNAs to Proteins
Prof. Katharina Hoefer, Prof. Andres Jaeschke
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Q3
Antibody Clamp: Restricting Antibody Fab Arm Flexibility for Enhanced Therapeutic Agonism
Prof. Mark Cragg, Dr Isabel Elliott, Dr Hayden Fisher, Prof. Ivo Tews, Prof. Jonathan Essex