TECHNOLOGIES 2018
Technologies marked with an * have been presented orally.
Industry
Cardiovascular
- P5SMECS - Small molecules for selective elimination of contaminating pluripotent stem cells from cultures of their differentiated derivatives
Prof. Albrecht Berkessel, Dr Tomo Saric, Karsten Burkert, Prof. Jürgen Hescheler
- W4Synthetic lignans targeting cardiovascular diseases
Prof. Marko Mihovilovic, Dr Thomas Linder, Prof. Verena M. Dirsch, Dr David Bernhard, Prof. Hermann Stuppner
Device
- I2Atomizer – new technology for production of micro- and nanoparticles
Miloš Beran, Dr Josef Drahorád, Zdenek Husek
Diagnostics
- R2*A method for early diagnosis of pancreatic cancer
Download PresentationProf. Michal Holčapek, Dr Eva Cífková, Dr Miroslav Lísa, Dr Denise Wolrab, Dr Robert Jirásko
- Z6Biomarker for the assessment of physical fitness
Prof. Jessica Bertrand, Prof. Christoph Lohmann, Karsten Pinno, Dr Margit Rudolf
- W3BioPersMed Metabolic and Cardio Cohort
Prof. Albrecht Schmidt, Prof. Barbara Obermayer-Pietsch
- B1*CD1a as a diagnostic marker and therapeutic target for Ulcerative Colitis
Download PresentationDr Roswitha Gropp, Prof. Matthias Siebeck, Michael Föhlinger, Dr Pia Palamides
- A2Diagnosing osteoporosis with CortBS
Prof. Kay Raum, Dr Juan Du, Gianluca Iori
- G3*Diagnosis/monitoring of glioblastoma and acute myeloid leukemia by (D)-2-hydroxyglutarate test (P-977)
Download PresentationProf. Andreas von Deimling, Dr Stefan Pusch, Dr Jörg Balss
- Z3Highly selective modification and detection of epigenetic target nucleobases via tailored TALEs
Prof. Daniel Summerer, Grzegorz Kubik, Sara Maurer, Mario Gieß
- Z9*Integrated platform for liquid biopsy-based personalized cancer medicine
Download PresentationDr Kamran Honarnejad, Dr Stefan Kirsch, Prof. Christoph Klein, Dr Bernhard Polzer, Dr Christian Werno
- Z2Marker-free, high-content screening for digital pathology
Prof. Rudolf Kessler, Dr Edwin Ostertag, Jörg-Walter Bartsch, Rainer Ritz
- N2*New diagnostic method for colorectal cancer
Download PresentationDr Rossella Solmi, Dr Mattia Lauriola, Dr Giampaolo Ugolini, Dr Isacco Montroni, Dr Maria Teresa Rodia, Dr Gabriella Mattei
- R1New highly selective interface for phosphoproteome profiling
Prof. Zuzana Bílková, Dr Jan Macák, Rudolf Kupčik, Dr Pavel Řehulka
Digital Health
- N4*Wound Viewer: system for monitoring chronic wounds
Download PresentationDr Jacopo Secco, Dr Marco Farina
Immune/Autoimmune
- Z4*
- L3Small molecules MALT1 inhibitors as therapeutics for B cell lymphoma and inflammation
Prof. Margot Thome, Dr Ming Zhang, Dr Barbara Saxty, Dr Sururat Adigun, Dr Lisa Hale
Infection
- P4*
- B2*Chemical disruption of the ClpX chaperone complex inhibits multiresistant Staphylococcus aureus virulence
Download PresentationDr Christian Fetzer, Dr Vadim Krotokov, Prof. Stephan Sieber
- D1*Clinical development of a therapeutic antibody (anti-pOxi D3) against antibiotic resistant Staphylococcus aureus (StaphAcute)
Download PresentationProf. Martin Krönke, Dr Alexander Klimka
- D5*Corallopyronin A – an antibiotic active against Helminths, Staphylococci and STIs
Download PresentationProf. Achim Hoerauf, Dr Stefan Kehraus, Prof. Gabriele Maria König, Dr Kenneth Pfarr, Dr Andrea Schiefer
- D3*Cystobactamide – novel antibacterials against gram-negative pathogens
Prof. Rolf Müller, Prof. Rolf Hartmann, Prof. Andreas Kirschning, Prof. Mark Brönstrup
- P3EF-Tu-binding Re-complex antibiotics
Prof. Nils Metzler-Nolte, Prof. Julia Bandow, Sina Schäkermann, Daniel Siegmund
- D4HY-133 – a novel decolonization agent for nasal S. aureus
Dr Wolfgang Mutter, Dr Sonja Molinaro
- P1Novel anti-tuberculosis compounds
Dr Oliver Koch, Luis Bering
- A4*Novel treatment for septic diseases in newborns
Prof. Dorothee Viemann, Prof. Johannes Roth, Prof. Thomas Vogl
- G1*Safe and effective preventative Epstein-Barr Virus (EBV) vaccine (P-989/1309)
Prof. Henri-Jacques Delecluse, Dr Anatoliy Shumilov, Ming-Han Tsai
- W1*Treatment of Sepsis and Acute Respiratory Distress Syndrome (ARDS)
Download PresentationProf. Valery Bochkov, Dr Olga Oskolkova
Metabolism
- L2*Matriptase inhibitor for utility in Osteoarthritis as disease modifying therapy
Download PresentationDr Drew Rowan, Dr Tim Chapman, Dr Lorna Duffy, Dr Prem Meghani
Neurology
- L1A humanised antibody that specifically targets truncated/toxic species of Aβ for Alzheimer’s Disease
Prof. Thomas Bayer, Dr David Matthews, Dr Janet Brownlees, Dr Preeti Bakrania
- E1A photoablation approach for the treatment of chronic pain and itch
Dr Paul Heppenstall
- C2Benzothiazole-based ureas as potential ABAD/17beta-HSD10 modulators for Alzheimer’s disease treatment
Dr Kamil Musílek, Dr Ondřej Benek, Dr Lukáš Hroch
- A3*Dipeptide repeat specific antibodies as immunotherapeutic option to treat C9orf72 patients
Prof. Dieter Edbauer, Prof. Christian Haass, Dr Kohji Mori, Dr Thomas Arzberger, Dr Elisabeth Kremmer
- Z8S-Oxprenolol for treating amyotrophic lateral sclerosis (ALS)
Dr Jochen Springer, Prof. Stefan Anker, Prof. Andrew Coats
- N1Stem cell extracellular vesicles to turn off ischemic inflammation
Dr Lorenza Lazzari, Dr Mario Barilani
- I1*Steroids as allosteric modulators of NMDAR for neuropathic pain treatment
Download PresentationDr Eva Kudová, Prof. Ladislav Vyklický, Dr Jiří Paleček
- C1Tacrine derivative as a potent and selective GLU2b antagonist for the treatment of neurodegenerative diseases
Dr Jan Korábečný, Dr Ondřej Soukup, Dr Martin Horák, Dr Karel Valeš
Oncology
- T1A new strategy for the treatment of Fibrosis related diseases
Prof. Donald Gullberg
- B3*CXCR6-transduced T cells for targeted tumor therapy
Dr Sebastian Kobold, Prof. Stefan Endres, Moritz Rapp, Simon Grassmann
- C3Enhancing effect of ATM/ATR/DNA-PK inhibitors on oncology treatment with standard chemotherapeutics
Dr Jan Korábečný, Dr Martin Andrš, Dr Ondřej Soukup, Prof. Martina Řezáčová, Dr Martina Seifrtová
- M5*Immunoproteasome inhibitors
Dr Robert Huber, Dr Uwe Koch, Dr Bert Klebl
- P2Inhibition of IKK complex
Prof. Christian Kaltschmidt, Prof. Barbara Kaltschmidt, Dr Johannes Greiner, Carsten Slotta, Jonathan Storm
- A1*Innovative nerve sheath tumor therapy
Dr Alexander Schulz, Dr Helen Morrison
- N5Nanoconstruct for antitumor therapy
Dr Valentina Cauda, Dr Giancarlo Canavese, Dr Nadia Garino, Dr Marco Laurenti, Dr Luisa Racca, Dr Andrea Ancona, Dr Marta Canta, Dr Bianca Dumontel, Dr Tania Limongi
- M4New inhibitors of Exon 20 mutations
Dr Roman Thomas, Dr Daniel Rauh, Dr Carsten Schulz-Fademrecht, Dr Bert Klebl
- W5Novel chalcone derivative for cancer treatment
Dr Katrina Vanura, Prof. Ulrich Jäger, Prof. Thomas Erker, Dr Gerda Brunhofer-Bolzer
- G2Peptide vaccine for treatment of IDH1 R132H mutant-positive cancers (P-987)
Prof. Michael Platten, Prof. Wolfgang Wick, Dr Theresa Schuhmacher
- M3Therapeutic Interleukin 11 antibody
Dr Reimar Abraham, Dr Johannes Bange, Prof. Matthias Ernst, Dr Tracy Putoczki
Others
- Z7*Chemokine-loaded microparticles in hyaluronic acid for treatment of osteoarthritis
Download PresentationDr Jochen Ringe, Dr Kristin Fröhlich, Prof. Michael Sittinger
- N3Electrospun nanofibrous multiscale scaffold for tendon and ligament tissue regeneration and replacement
Dr Alberto Sensini, Dr Luca Cristofolini, Dr Chiara Gualandi, Dr Maria Letizia Focarete, Dr Juri Belcari, Dr Andrea Zucchelli
- K1*Treatment of PCOS or oligo-ovulatory androgen excess in women
Download PresentationProf. Francis De Zegher, Prof. Lourdes Ibanez
Tools
- E2A novel Sleeping Beauty transposase system for development of gene therapies
Dr Orsolya Barabas
- A5*Homology independent genomic sequence replacement
Dr Ralf Kühn, Eric Danner
- Z1Innovative method for detecting co-occurring histone modifications in a single step using hybrid proteins
Prof. Albert Jeltsch, Goran Kungulovski, Rebekka Mauser
- Z5Low cost cloning
Dr Sylvestre Marillonnet
- M1Methods to drastically increase precise genome editing efficiency with CRISPR enzymes in stem cells and various mammalian cells
Dr Tomislav Maricic, Stephan Riesenberg